Hepatitis B Virus
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چکیده
The structure of hepatitis B virus (HBV) has been characterized in great detail (Tiollais & Buendia, 1991). HBV belongs to a group of hepatotropic DNA viruses (hepadnaviruses) that includes the hepatitis viruses of the woodchuck (Summers et al., 1978), ground squirrel (Marion et al., 1980), Pekin duck (Mason et al., 1980) and heron (Sprengel et al., 1988). HBV is a smaII virus, about 42 nm in diameter ('Dane particle'), composed of a lipidbilayer envelope containing hepatitis B surface antigen (HBsAg) and an internai nucleocapsid structure (core). The nucleocapsid consists of the core protein and the viral DNA genome, which is about 3200 base pairs (about 2100 kDa) in length, with an associated DNA polymerase/reverse transcriptase (Tiollais et al., 1985; Blum et al., 1989a).
منابع مشابه
Molecular detection of hepatitis delta virus in blood donors with RT-PCR
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